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DR. Roland Schulze
promovierteR Biologe


Quellen & Studien
- DGE - Deutsche Gesellschaft für Ernährung (2018): Sekundäre Pflanzenstoffe und ihre Wirkung auf die Gesundheit.
https://www.dge.de/wissenschaft/weitere-publikationen/fachinformationen/sekundaere-pflanzenstoffe-und-ihre-wirkung/ - Weiß, C. (2007): Glykoalkaloide in Kartoffeln und Tomaten. Ernährungs Umschau, 8: 474-477.
https://www.ernaehrungs-umschau.de/fileadmin/Ernaehrungs-Umschau/pdfs/pdf_2007/08_07/EU08_474_477.qxd.pdf - Sakurai, K., Sawamura, T. (2003): Stress and vascular responses - endothelial dysfunction via lectin-like oxidized low-density lipoprotein receptor-1 - close relationships with oxidative stress. J Pharmacol Sci, 91(3): 182-186.
https://www.ncbi.nlm.nih.gov/pubmed/12686739 - Pruimboom, L., de Punder, K. (2015): The opioid effects of gluten exorphins - asymptomatic celiac disease. J Health Popul Nutr, 33: 24.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025969/ - Liu, S., Stampfer, MJ., Hu, FB., Giovannucci, E., Rimm, E., Manson, JE., Hennekens, CH., Willett, WC. (1999): Whole-grain consumption and risk of coronary heart disease - results from the Nurses’ Health Study. Am J Clin Nutr, 70(3): 412-419.
https://www.ncbi.nlm.nih.gov/pubmed/10479204 - Liu, S., Manson, JE., Stampfer, MJ., Hu, FB., Giovannucci, E., Colditz, GA., Hennekens, CH., Willett, WC. (2000): A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US women. Am J Public Health, 90(9): 1409-1415.
https://www.ncbi.nlm.nih.gov/pubmed/10983198 - Jonnalagadda, SS., Harnack, L., Liu, RH., McKeown, N., Seal, C., Liu, S., Fahey, GC. (2011): Putting the whole grain puzzle together - health benefits associated with whole grains -- summary of American Society for Nutrition 2010 Satellite Symposium. J Nutr, 141(5): 1011-1022.
https://www.ncbi.nlm.nih.gov/pubmed/21451131 - Geo online (2018): Von Soja, Fleisch und dem besseren Leben.
https://www.geo.de/natur/oekologie/11033-bstr-von-soja-fleisch-und-dem-besseren-leben/153887-img-exportschlager-soja - FAO - Ernährungs- und Landwirtschaftsorganisation der vereinten Nationen (2018): Production/Yield quantities of Soybeans in World. http://www.fao.org/faostat/en/#data/QC/visualize
- Ward, HA., Kuhnle, GG., Mulligan, AA., Lentjes, MA., Luben, RN., Khaw, KT. (2010): Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database. Am J Clin Nutr, 91(2): 440-448.
https://www.ncbi.nlm.nih.gov/pubmed/20007303 - BfR - Bundesinstitut für Risikobewertung (2007): Isolierte Isoflavone sind nicht ohne Risiko. Aktualisierte Stellungnahme Nr. 039/2007.
https://www.bfr.bund.de/cm/343/isolierte_isoflavone_sind_nicht_ohne_risiko.pdf - Chandra, AK. (2010): Bioactive Foods in Promoting Health. Academic Press, kapitel 42, S. 691-716.
https://www.sciencedirect.com/science/article/pii/B9780123746283000426 - Pandey, KB., Rizvi, SI. (2009): Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev, 2(5): 270-278.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835915/ - Khurana, S., Venkataraman, K., Hollingsworth, A., Piche, M., Tai, TC. (2013): Polyphenols - Benefits of the Cardiovascular System in Health and in Aging. Nutrients, 5(10): 3779-3827.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820045/ - Basu, A., Rhone, M., Lyons, TJ. (2010): Berries - emerging impact on cardiovascular health. Nutr Rev, 68(3): 168-177.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068482/ - Most, J., Goossens, GH., Jocken, JW., Blaak, EE. (2014): Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects. Int J Obes (Lond), 38(5): 198-706.
https://www.ncbi.nlm.nih.gov/pubmed/24317366 - Teng, Y., Wu, D. (2017): Anti-Fatigue Effect of Green Tea Polyphenols (-)-Epigallocatechin-3-Gallate (EGCG). Pharmacogn mag, 13(50): 326-331.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421434/ - Hussain, T., Tan, B., Yin, Y., Blachier, F., Tossou, MCB., Rahu, N. (2016): Oxidative Stress and Inflammation - What Polyphenols Can Do for Us? Oxid Med Coll Longev, 2016: 7432797.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055983/ - Cuevas, A., Saavedra, N., Salazar, LA., Abdalla, DSP. (2013): Modulation of Immune Function by Polyphenols - Possible Contribution of Epigenetic Factors. Nutrients, 5(7): 2314-2332.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738975/ - Nichols, JA., Katiyar, SK. (2010): Skin photoprotection by natural polyphenols - anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res, 302(2): 71.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813915/ - Guo, X., Tresserra-Rimbau, A., Estruch, R., Martinez-González, MA., Medina-Remón, A., Fitó, M., Corella, D., Salas-Salvadó, J., Portillo, MP., Moreno, JJ., Pi-Sunyer, X., Lamuela-Raventós, RM. (2017): Polyphenol Levels Are Inversely Correlated with Body Weight and Obesity in an Elderly Population after 5 Years of Follow Up (The Randomised PREDIMED Study). Nutrients, 9(5): 452.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452182/ - Shen, CL., Smith, BJ., Lo, DF., Chyu, MC., Dunn, DM., Chen, CH., Kwun, IS. (2012): Dietary polyphenols and mechanisms of osteoarthritis. J Nutr Biochem, 23(11): 1367-1377.
https://www.ncbi.nlm.nih.gov/pubmed/22832078 - Kim, Y., Keogh, JB., Clifton, PM. (2016): Polyphenols and Glycemic Control. Nutrients, 8(1): 17.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728631/ - Bell, L., Lamport, DJ., Butler, LT., Williams, CM. (2015): A Review of the Cognitive Effects Observed in Humans Following Acute Supplementation with Flavonoids, and Their Associated Mechanisms of Action. Nutrients, 7(12): 10290-10306.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690090/ - American Chemical Society (1998): Eating Berries Can Help Lower LDL Cholesterol. Science News.
https://www.sciencedaily.com/releases/1998/10/981005074625.htm - Pandey, KB., Rizvi, SI. (2009): Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Coll Longev, 2(5): 270-278.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835915/ - Most, J., Goossens, GH., Jocken, JW., Blaak, EE. (2014): Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects. Int J Obes (Lond), 38(5): 698-706.
https://www.ncbi.nlm.nih.gov/pubmed/24317366 - Basu, A., Rhone, M., Lyons, TJ. (2010): Berries - emerging impact on cardiovascular health. Nutr Rev, 68(3): 168-177.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068482/ - Kim, Y., Keogh, JB., Clifton, PM. (2016): Polyphenols and Glycemic Control. Nutrients, 8(1): 17.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728631/ - Tresserra-Rimbau, A., Rimm, EB., Medina-Remón, A., Martinez-González, MA., López-Sabater, MC., Covas, MI., Corella, D., Salas-Salvadó, J., Gómez-Gracia, E., Lapetra, J., Arós, F., Fiol, M., Ros, E., Serra-Majem, L., Pintó, X., Munoz, MA., Gea, A., Ruiz-Gutiérrez, V., Estruch, R., Lamuela-Raventós, RM., PREDIMED Study Investigators (2014): Polyphenol intake and mortality risk - a re-analysis of the PREDIMED trial. BMC Med, 12: 77.
https://www.ncbi.nlm.nih.gov/pubmed/24886552 - Kim, B., Bae, M., Park, YK., Ma, H., Yuan, T., Seeram, NP., Lee, JY. (2018): Blackcurrant anthocyanins stimulated cholesterol transport via post-transcriptional induction of LDL receptor in Caco-2 cells. Eur J Nutr, 57(1): 405-415.
https://www.ncbi.nlm.nih.gov/pubmed/28718016 - Qin, Y., Xia, M., Ma, J., Hao, Y., Liu, J., Mou, H., Cao, L., Ling, W. (2009): Anthocyanin supplementation improves serum LDL- and HDL-cholesterol concentrations associated with the inhibition of cholesteryl ester transfer protein in dyslipidemic subjects. Am J Clin Nutr, 90(3): 485-492.
https://www.ncbi.nlm.nih.gov/pubmed/19640950 - Menayang, A. (2016): Study finds berry pigments may decrease bad cholesterol in overweight individuals. Nutra Ingredients.
https://www.nutraingredients-usa.com/Article/2016/01/20/Anthocyanins-may-decrease-bad-cholesterol-in-overweight-individuals - WHO - Weltgesundheitsorganisation (2017): Cardiovascular diseases (CVDs). http://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)
- Parkar, SG., Trower, TM, Stevenson, DE. (2013): Fecal microbial metabolism of polyphenols and its effects on human gut microbiota. Anaerobe, 23: 12-19.
https://www.sciencedirect.com/science/article/pii/S1075996413001303?via%3Dihub - Parkar, SG., Stevenson, DE., Skinner, MA. (2008): The potential influence of fruit polyphenols on colonic microflora and human gut health. Int J Food Microbiol, 124(3): 295-298.
https://www.sciencedirect.com/science/article/pii/S0168160508001402 - Vendrame, S., Gugliemetti, S., Riso, P., Arioli, S., Klimis-Zacras, D., Porrini, M. (2011): Six-Week Consumption of a Wild Blueberry Powder Drink Increases Bifidobacteria in the Human Gut. A Agric Food Chem, 59(24): 12815-12820.
https://pubs.acs.org/doi/abs/10.1021/jf2028686 - Duenas, M., Munoz-González, I., Cueva, C., Jiménez-Girón, A., Sánchez-Patán, F., Santos-Buelga, C., Moreno-Arribas, MV., Bartolomé, B. (2015): A Survey Modulation of Gut Microbiota by Dietary Polyphenols. Biomed Res Int, 2015: 850902.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352430/ - Zheng, W., Wang, SY. (2003): Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries. J Agric Food Chem, 51(2): 502-509.
https://www.ncbi.nlm.nih.gov/pubmed/12517117 - Varela, CE., Fromentin, E., Roller, M., Villarreal, F., Ramirez-Sanchez, I. (2016): Effects of a natural extract of Aronia Melanocarpa berry on endothelial cell nitric oxide production. J Food Biochem, 40(4): 404-410.
https://www.ncbi.nlm.nih.gov/pubmed/27616799 - Kedzierska, M., Olas, B., Wachowicz, B., Glowacki, R., Bald, E., Czernek, U., Szydlowska-Pazera, K., Potemski, P., Piekarski, J., Jeziorski, A. (2012): Effects of commercial extract of aronia on oxidative stress in blood platelets isolated from breast cancer patients after the surgery and various phases of the chemotherapy. Fitoterapia, 83(2): 310-317.
https://www.ncbi.nlm.nih.gov/pubmed/22101070?dopt=Abstract - Paquette, M., Larqué, ASM., Weisnagel, SJ., Desjardins, Y., Marois, J., Pilon, G., Dudonné, S., Marette, A., Jacques, H. (2017): Strawberry and cranberry polyphenols improve insulin sensitivity in insulin-resistant, non-diabetic adults - a parallel, double-blind, controlled and randomised clinical trial. Br J Nutr, 117(4): 519-531.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426341/ - McKay, DL, Blumberg, JB. (2007): Cranberries (Vaccinium macrocarpon) and cardiovascular disease risk factors. Nutr Rev, 65(11):490-502.
https://www.ncbi.nlm.nih.gov/pubmed/18038941 - Khoo, C., Falk, M. (2014): Cranberry Polyphenols: Effects on Cardiovascular Risk Factors. Polyphenols in Human Health and Disease, 2: 1049–1065.
https://www.sciencedirect.com/science/article/pii/B9780123984562000815 - Jenkins, DJ., Nguyen, TH., Kendall, CW., Faulkner, DA., Bashyman, B., Kim, IJ., Ireland, C., Patel, D., Vidgen, E., Josse, AR., Sesso, HD., Burton-Freeman, B., Josse, RG., Leiter, LA., Singer, W. (2008): The effect of strawberries in a cholesterol-lowering dietary portfolio. Metabolism, 57(12): 1636-1644.
https://www.ncbi.nlm.nih.gov/pubmed/19013285 - Zhang, H., Ma, ZF., Luo, X., Li, X. (2018): Effects of Mulberry Fruit (Morus alba L.) Consumption on Health Outcomes - A Mini-Review. Antioxidants (Basel), 7(5): 69.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981255/ - Ferrières, J. (2004): The French paradox - lessons for other countries. Heart, 90(1): 107-111.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1768013/ - Haller, D., Grune, T., Rimbach, G. (2013): Biofunktionalität der Lebensmittelinhaltsstoffe. Springer Verlag, S. 212.
- Mbikay, M. (2012): Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia - A Review. Front Pharmacol, 3: 24.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290775/ - Gopalakrishnan, L., Doriya, K., Kumar, DS. (2016): Moringa oleifera - A review on nutritive importance and its medicinal application. Food Sci Human Well, 5(2): 49-56.
https://www.sciencedirect.com/science/article/pii/S2213453016300362 - Danesi, F., Ferguson, LR. (2017): Could Pomegranate Juice Help in the Control of Inflammatory Diseases? Nutrients, 9(9): 958.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622718/ - Colombo, E., sangiovanni, E., Dell’Agli, M. (2013): A Review on the Anti-Inflammatory Activity of Pomegranate in the Gastrointestinal Tract. Evid Based Complement Alternat Med, 2013: 247145.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612487/ - Cooper, EL., Ma, MJ. (2017): Understanding nutrition and immunity in disease management. J Traditio Compl Med, 7(4): 386-391.
https://www.sciencedirect.com/science/article/pii/S2225411016303029 - Ishola, IO., Awodele, O., Olusayero, AM., Ochieng, CO. (2014): Mechanisms of analgesic and anti-inflammatory properties of Annona muricata Linn. (Annonaceae) fruit extract in rodents. J Med Food, 17(12): 1375-1382.
https://www.ncbi.nlm.nih.gov/pubmed/25133801 - George, VC., Kumar, DRN., Suresh, PK., Kumar, RA. (2015): Antioxidant, DNA protective efficacy and HPLC analysis of Annona muricata (soursop) extracts. J Food Sci Technol, 52(4): 2328-2335.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375238/ - Kim, GT., Tran, NKS., Choi, E., Song, Y., Song, J., Shim, S., Park, T. (2016): Immunomodulatory Efficacy of Standardized Annona muricata (Graviola) Leaf Extract via Activation of Mitogen-Activated Protein Kinase Pathways in RAW 264.7 Macrophages. Evid Based Complement Alternat Med, 2016: 2905127.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209628/ - Barolo, MI., Ruiz Mostacero, N., López, SN. (2014): Ficus carica L. (Moracerae) - an ancient source of food and health. Food Chem, 164: 119-127.
https://www.ncbi.nlm.nih.gov/pubmed/24996314 - Clifford, T., Howatson, G., West, DJ., Stevenson, EJ. (2015): The Potential Benefits of Red Beetroot Supplementation in Health and Disease. Nutrients, 7(4): 2801-2822.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425174/ - Chinwong, S., Chinwong, D., Mangklabruks, A. (2017): Daily Consumption of Virgin Coconut Oil Increases High-Density Lipoprotein Cholesterol Levels in Healthy Volunteers: A Randomized Crossover Trial. Evid Based Complement Alternat Med, 7251562.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745680/ - Tursun, X., Zhao, Y., Talat, Z., Xin, X., Tursun, A., Abdulla, R., Aisa, HA. (2016): Anti-Inflammatory Effect of Rosa rugosa Flower Extract in Lipopolysaccharide-Stimulated RAW264.7 Macrophages. Biomol Ther (Seoul), 24(2): 184-190.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774500/ - Loftus, HL., Astell, KJ., Mathai, ML., Su, XQ. (2015): Coleus forskholii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects - A Randomized Controlled Trial. Nutrients, 7(11): 9508-9522.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663611/ - Fukuchi, Y. Hiramitsu, M., Okada, M., Hayashi, S., Nabeno, Y., Osawa, T., Naito, M. (2008): Lemon Polyphenols Suppress Diet-induced Obesity by Up-Regulation of mRNA Levels of the Enzymes Involved in ß-Oxidation in Mouse White Adipose Tissue. J Clin Biochem Nutr, 43(3): 201-209.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581754/ - Burton-Freeman, BM., Sandhu, AK., Edirisinghe, I. (2016): Red Raspberries and Their Bioactive Polyphenols - Cardiometabolic and Neuronal Health Links. Adv Nutr, 7(1): 44-65.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717884/ - Magistrelli, A., Chezem, JC. (2012): Effect of ground cinnamon on postprandial blood glucose concentration in normal-weight and obese adults. J Acad Nutr Diet, 112(11): 1806-1809.
https://www.ncbi.nlm.nih.gov/pubmed/23102179 - Hartz, AJ., Bentler, S., Noyes, R., Hoehns, J., Logemann, C., Sinift, S., Butani, Y., Wang, W., Brake, K., Ernst, M., Kautzman, H. (2004): Randomized controlled trial of Siberian ginseng for chronic fatigue. Psychol Med, 34(1): 51-61.
https://www.ncbi.nlm.nih.gov/pubmed/14971626/ - Panossian, A., Wikman, G. (2009): Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol, 4(3): 198-219.
https://www.ncbi.nlm.nih.gov/pubmed/19500070 - Jung, CH., Jung, H., Shin, YC., Park, JH., Jun, CY., Kim, HM., Yim, HS., Shin, MG., Bae, HS., Kim, SH., Ko, SG. (2007): Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage. J Ethnopharmacol, 113(1): 183-187.
https://www.ncbi.nlm.nih.gov/pubmed/17644291 - Ahn, J., Um, MY., Lee, H., Jung, CH., Heo, SH., Ha, TY. (2013): Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice. Evid Based Complement Alternat Med, 2013: 934183.
https://www.ncbi.nlm.nih.gov/pubmed/23690865 - Wesnes, KA., Ward, T., McGinty, A., Petrini, O. (2000): The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers. Psychopharmacology (Berl), 152(4): 353-361.
https://www.ncbi.nlm.nih.gov/pubmed/11140327 - Field, BH., Vadnal, R. (1998): Ginkgo biloba and Memory - An Overview. Nutr Neurosci, 1(4): 255-267.
https://www.ncbi.nlm.nih.gov/pubmed/27414695 - Cieza, A., Maier, P., Pöppel, E. (2003): Effects of Ginkgo biloba on mental functioning in healthy volunteers. Arch Med Res, 34(5): 373-381.
https://www.ncbi.nlm.nih.gov/pubmed/14602503 - Kaschel, R. (2011): Specific memory effects of Ginkgo biloba extract EGb 761 in middle-aged healthy volunteers. Phytomedicine, 18(14): 1202-1207.
https://www.ncbi.nlm.nih.gov/pubmed/21802920 - Haghighi, M., Khalvat, A., Toliat, T., Jallaei, S. (2005): Comparing the effects of ginger (zingiber officinale) extract and ibuprofen on patients with osteoarthritis. Arch Iranian Med, 8(4): 267-271.
https://www.researchgate.net/publication/235007127_Comparing_the_Effects_of_ginger_Zingiber_officinale_extract_and_ibuprofen_On_patients_with_osteoarthritis - NHV Theophrastus (2018): Ingwer - Heilpflanze des Jahres 2018.
http://www.nhv-theophrastus.de/artikel/000058/l1690741797/index.html - Adam, O., Schauder, P., Ollenschläger, G. (2006): Ernährungsmedizin - Prävention und Therapie. 3. Auflage. Elsevier, Urban & Fischer Verlag, S. 463.
- Westerterp-Plantenga, MS., Lejeune, MP., Kovacs, EM. (2005): Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation. Obes Res, 13(7): 1195-1204.
https://www.ncbi.nlm.nih.gov/pubmed/16076989 - Teng, YS., Wu, D. (2017): Anti-Fatigue Effect of Green Tea Polyphenols (-)-Epigallocatechin-3-Gallate (ECGC). Pharmacogn Mag, 13(50): 326-331.
https://www.ncbi.nlm.nih.gov/pubmed/28539729 - Basu, A., Sanchez, K., Leyva, MJ., Wu, M., Betts, NM., Aston, CE., Lyons, TJ. (2010): Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome. J Am Coll Nutr, 29(1): 31-40.
https://www.ncbi.nlm.nih.gov/pubmed/20595643 - Jehle, S., Dittrich, K. (2018): Ist Matcha-Tee gesünder als grüner Tee? UGB - Vereine für Unabhängige Gesundheitsberatung e.V.
https://www.ugb.de/exklusiv/fragen-service/matcha-gruentee/?matcha-tee-gruener-tee